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biotechniques.com
Nanopore sequencing: how does it work?
Oxford Nanopore sequencing devices use flow cells that contain tiny holes – nanopores – embedded in an electro-resistant membrane. When DNA passes through a nanopore, the current is disrupted, producing a ‘squiggle’ that is specific to the particular base that has passed through in that moment. These squiggles can be decoded using ...
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